Florida State vs. Clemson Week 10 College Football Picks: In what is the game of the week out of the ACC the Clemson Tigers will host the Florida State Seminoles at 7:45 PM ET. The winner of this physical match-up will stay in the mix to play in the ACC title game. After their upset win over Miami, Clemson (5-3) spanked Coastal Carolina 49-3 in a game that was off the NCAA football betting board. FSU (4-4) won a closer than anticipated shootout last week to N.C State 45-42 as -10.5 home favorites.


The Florida State vs. Clemson Week 10 College Football Picks NCAA Football betting spread is -9 at Sportsbetting.com.

Clemson Tigers Offense vs. Florida State Seminoles Defense: Clemson’s 31st ranked offense boasts one of the finest players in the country in 5’11” 190 Lb. RB C.J Spiller (841 yds, 5.1, 6 td). FSU’s speedy defense has been a major disappointment this season ranking 93rd in points allowed. FSU’s defense ranks last against the run and pass in the ACC and will be at a disadvantage against Clemson’s offense that has improved in the passing game in recent outings. The Florida State vs. Clemson Week 10 College Football Picks NCAA Football betting Total is at 58.5 points.
 
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Florida State Seminoles Offense vs. Clemson Tigers Defense: FSU’s 26th ranked offense is led by QB Christian Ponder (2617 yds, 69.4%, 15-3 ratio) who is nursing sore ribs and will not be 100% healthy. Clemson’s swarming defense ranks 16th in the country and has a ferocious pass-defense led by NFL prospect DE Ricky Sapp. FSU’s run game came to life last week but they still prefer to throw the ball which plays into Clemson’s strength on defense. Advantage Clemson.

Intangibles: Clemson is 9-3 ATS in their last 12 games. Home team is 10-1 ATS in their last 11 games. FSU won last year 41-27 s -3.5 home favorites. Clemson has a solid edge on special teams.