Vanderbilt vs Florida Week 10 College Football Picks: The Florida Gators are already locked into the SEC championship game but their focus is still on the BCS championship as they host Vanderbilt Saturday night at 7:15 PM ET. Florida (8-0) is coming off the best performance of their season when they blew away Georgia 41-17 as -16.5 home favorites. Vanderbilt (2-7) continued to disappoint with a 31-56 defeat to Georgia Tech as +13 home underdogs for their 5th straight loss.
 

The Vanderbilt vs Florida Week 10 College Football Picks College Football Betting spread is Florida -35 points at Sportsbook.com
 
Analysis: The Florida Gators will be missing All-American LB Brandon Spikes for a half quarter Saturday for a supposed eye gouging incident against Georgia. Florida head coach Urban Meyer had this to say about the Spikes half game suspension: "I don't condone that. I understand what goes on on the football (field), but there's no place for that. That's not who he is. That's not who we are." Florida will try to avoid a letdown after last week’s resounding win over Georgia. The Vanderbilt vs Florida Week 10 College Football Picks College Football Betting Total is at 46.0 points.
 
Vanderbilt will turn to their backup QB Mackenzi Adams to lead the team against the Gators after starter Larry Smith hurt his hamstring last week. Vanderbilt head coach Bobby Johnson had this to say about his young quarterback: "Mackenzi won't be scared. He'll be confident and he'll plan on going out there and making every throw and every read. We expect him to meet the challenge and play well this week, and we certainly hope he will."
 
Begin your College Football Betting with our week 10 college football picks at Sportsbook.com and receive a 50% Sign Up Bonus and $50 FREE BET!!
 
Florida has the big edge on both sides of the ball especially at QB with Tim Tebow (10-4 ratio, 64.7%, 1323 yd pass, 551 yd rush 8 td)  playing much better since his head injury about a month ago. Florida has a huge edge on offense (#6-#110). Florida also has the decided edge on defense (#2-#42). Special teams also fall in the Florida Gators favor by a wide margin (#13-#93).
 
Intangibles: Florida is 3-5 ATS. Vanderbilt is 4-3 ATS. Vanderbilt is 8-3 ATS in their last 11 road games. Florida is 21-7 ATS in their last 28 games. Florida has won 18 straight SU against Vandy. Florida beat Vanderbilt 42-14 last year as -24 away favorites. Florida has a +5 point home field advantage.