For the NFL Picks Week 10 match-up between the Bills vs Titans, we turned to the NFL Handicapping experts to get their insight and hopefully a few free sports picks. The opening point spread had the Tennessee Titans -6 ½ (-110 odds) against the Buffalo Bills. Currently, the best NFL point spreads to Bet the Titans is at BetUS and SBG Global, you can get Tennessee -8 (-110 odds).

“This isn't exactly the "Music City Miracle," as Buffalo and Tennessee have matched up just three times in the regular season since 2000. The Titans are slowly heating up, capturing back-to-back victories over the Jaguars and Niners. The Bills are languishing at 3-5 inside the AFC East, coming off an embarrassing home loss to the Texans prior to the bye week,” stated VegasInsider.com NFL Handicapping Expert Kevin Rogers about the Bills vs Titans NFL Week 10 match up. “Many teams this week are good plays off the bye, and that includes the Bills. Buffalo has covered each of its last four after their off week, including all three in the Dick Jauron era. The Bills are a profitable 5-1 ATS the last six as a road underdog, including a 3-1 ATS mark this season.”

The best NFL point spreads to Bet the Bills is at Bodog.com and Sportsbook.com, you can get Buffalo +8 ½ (-110 odds). Kickoff is scheduled at 1:05 PM EST between the Bills vs Titans NFL Picks Week 10 match up.

Rogers further stated, “The Titans own a solid mark in a situation that applies this week. Tennessee is 15-2 ATS at home off a SU win playing a non-division opponent coming off an ATS loss. However, the Titans are only 5-6 ATS the last three seasons off a road win.”

The opening number on the Buffalo Bills vs Tennessee Titans TOTAL was 41 points. The best place to bet the OVER is Sportsbook.com, you can get OVER 41 points. The best place to bet the UNDER is at BetUS.com, you can get UNDER 41 1/2 points.