Bills vs Lions Odds 2010 NFL Preseason Week 4: The Buffalo Bills (1-1) continue their fine tuning in their final preseason game against the Detroit Lions (1-1). The Bills took care of business last week against the Indianapolis Colts, 34-21 in a game that saw C.J. spiller rush for 50+ yards and a touchdown. The Lions topped the Denver Broncos, 25-20 in last weeks game in Denver. Hammerhead Sports always delivers the most accurate free sports picks and football odds from our team of NFL Predictions experts. Find our Winning NFL Picks selections below.

Trent Edwards furthered his bid to reclaim the starting quarterback job he lost midway through last season by going 5 for 8 for 93 yards, including a 70-yard touchdown pass to Lee Evans. The 14 points scored by Buffalo's first-stringers more than doubled the two field goals they had managed in their previous six preseason games, dating to last year. Rian Lindell hit a 24-yarder with 22 seconds left in the first half to put Buffalo ahead for good, 24-21. The Sportsbooks at Bodog.com have the Buffalo Bills (-2) as the Free NFL Picks selection over the Detroit Lions (+2).

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Matthew Stafford was 13 of 20 for 130 yards, guiding the Lions to scores on all four of their first-half drives. Top draft pick Ndamukong Suh was on the sideline for that last-minute drive, his day done after causing plenty of havoc along the Broncos' makeshift offensive line. Steven Hauschka, filling in while Jason Hanson recovers from minor knee surgery, kicked field goals of 28, 27, 29 and 27 yards after Detroit's offense repeatedly sputtered around the 10-yard line. The Lions will need to do a better job of finishing drives.With the NFL Betting Odds point total at 36, the Over seems like the smart play here.